麻豆传媒色情片

Profile

Finding a symphony among complex molecules

MOSAIC scholar uses total synthesis to recreate rare natural products with potential therapeutic applications
Jay Thakkar
April 23, 2025

Surrounded by the lakes and forests of northern Michigan’s Lower Peninsula, discovered a passion for music early on, despite a lack of formal training.

Stanna Dorn
Stanna Dorn (center) plays the flute and performs with the Caltech Wind Orchestra in 2024.

“Music was always a way to process emotion and express myself even when I didn’t have the chance to do that in other aspects,” Dorn said.

As a chemistry and music double major, she used music to escape the stresses of a scientific degree.

“Although it was incredibly challenging, I find that music provides a necessary balance in my life to the science,” Dorn said.

When she’d face obstacles in her chemistry coursework, Dorn turned to her flute, and vice versa.

Dorn graduated with a B.A. in music and B.S. in Chemistry from Hope College. She now has a Ph.D. in organic chemistry from Indiana University Bloomington and currently works as a postdoctoral researcher in lab at Caltech.

There, she works on total synthesis, a branch of organic chemistry focused on recreating complex molecules found in nature.

“Total synthesis is motivated by some natural source, for example — jellyfish produce a molecule that may have promising properties against some biological aspect that is interesting to study,” Dorn explained “But there are not enough jellyfish in the world to be able to meet the supply or to even test (this molecule). That is where synthetic chemists come in.”

Stanna Dorn
Stanna Dorn poses in front of her fume hood at Indiana University-Bloomington on the final day of her Ph.D. studies in 2022.

Dorn focuses on bacterial metabolites. Her goal is to amass enough of these natural products to study their interactions with proteins, nucleic acids and more.  

“We try to help access these molecules not only in an efficient way but also in a creative way in order to expand chemical knowledge about how we put molecules together.”

For this work, she received an 麻豆传媒色情片 and 麻豆传媒色情片 Biology’s Maximizing Opportunities for Scientific and Academic Independent Careers, or MOSAIC, award which supported postdocs and new investigators from diverse backgrounds who are embarking on careers at research-intensive institutions.

“The timing of the MOSAIC (was) meaningful to me because ten years ago I was taking intro to organic chemistry, and I almost failed out of it,” she said. “Organic chemistry has this reputation of being hard.”

Dorn’s future work will focus on creating novel methods to isolate and replicate bacterial metabolites of interest to human health. In her spare time, she still enjoys playing the flute and making music.

“Anytime you are working on a new method you are just exploring the unknown,” Dorn said.

Enjoy reading ASBMB Today?

Become a member to receive the print edition four times a year and the digital edition monthly.

Learn more
Jay Thakkar

Jay Thakkar is a researcher, who specializes in computer-aided drug design and discovery. He earned a bachelor's degree in chemical engineering from the Dwarkadas J. Sanghvi College of Engineering in Mumbai, India, and a master's degree in chemistry from the Stevens Institute of Technology in Hoboken, New Jersey, where he studied drug discovery. His hobbies include reading, driving on open roads and walking in the park.
 

Get the latest from ASBMB Today

Enter your email address, and we鈥檒l send you a weekly email with recent articles, interviews and more.

Latest in People

People highlights or most popular articles

How undergrad research catalyzes scientific careers
Essay

How undergrad research catalyzes scientific careers

Aug. 27, 2025

Undergraduate research doesn鈥檛 just teach lab skills, it transforms scientists. For Antonio Rivera and Julissa Cruz鈥揃autista, joining a lab became a turning point, fostering critical thinking, persistence and research identity.

Simcox and Gisriel receive mentoring award
Member News

Simcox and Gisriel receive mentoring award

Aug. 25, 2025

They were honored for contributing their time, knowledge, energy and enthusiasm to mentoring postdocs in their labs.

ASBMB names 2025 Marion B. Sewer scholarship recipients
Society News

ASBMB names 2025 Marion B. Sewer scholarship recipients

Aug. 21, 2025

Ten undergraduates interested in biochemistry and molecular biology will each receive $2,000 toward their tuition and related educational costs.

Attie named honorary professor
Member News

Attie named honorary professor

Aug. 18, 2025

This award includes $100,000 of research funding and recognizes faculty who have made major contributions to the advancement of knowledge through their research, teaching and service activities.

Meet the 2025 SOC grant awardees
Outreach

Meet the 2025 SOC grant awardees

Aug. 15, 2025

Five science outreach and communication projects received up to $1,000 from ASBMB to promote the understanding of molecular life science.

Unraveling cancer鈥檚 spaghetti proteins
Profile

Unraveling cancer鈥檚 spaghetti proteins

Aug. 13, 2025

MOSAIC scholar Katie Dunleavy investigates how Aurora kinase A shields oncogene c-MYC from degradation, using cutting-edge techniques to uncover new strategies targeting 鈥渦ndruggable鈥 molecules.